4-Chloro-6-methoxypyrimidin-2-amine
نویسندگان
چکیده
The title compound, C5H6ClN3O, is essentially planar with a maximum deviation of 0.0256 (11) Å for all non-H atoms. In the crystal, adjacent mol-ecules are linked by a pair of N-H⋯N hydrogen bonds, forming an inversion dimer with an R2(2)(8) ring motif. The dimers are further linked via N-H⋯O hydrogen bonds into an undulating sheet structure parallel to the bc plane.
منابع مشابه
4-Chloro-6-methoxypyrimidin-2-amine–succinic acid (2/1)
The asymmetric unit of the title compound, 2C5H6ClN3O·C4H6O4, consists of one 4-chloro-6-meth-oxy-pyrimidin-2-amine mol-ecule and one half-mol-ecule of succinic acid which lies about an inversion centre. In the crystal, the acid and base mol-ecules are linked through N-H⋯O and O-H⋯N hydrogen bonds, forming a tape along [1-10] in which R2(2)(8) and R4(2)(8) hydrogen-bond motifs are observed. The...
متن کاملCAS Name: 4-Chloro-2-methylbenzenamine Synonyms: 2-Amino-5-chlorotoluene; 3-chloro-6-aminotoluene; 4-chloro-2- methylaniline; 4-chloro-6-methylaniline; (4-chloro-2-methylphenyl)amine; 4-chloro-2-toluidine; 4-chloro-ortho-toluidine; 5-chloro-2-aminotoluene; para-chloro-ortho-toluidine; 2-methyl-4-chloroaniline; 2-methyl-4- chlorobenzeneamine
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Novel synthesis of Pyrimido[4,5- e] [1,3,4] thiadiazines
Treatment of 1-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-1-methylhydrazine with dimethylthiocarbamoylchloride gave 7-chloro-N,N,1,5-tetramethyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-amine in basic acetonitrile. The latter compounds were reacted with secondary amines in boiling ethanol to afford the related 7-amino derivatives.
متن کامل6-Chloro-4-(2-phenylethenyl)chroman-2-one
The title compound, C(17)H(13)ClO(2), was obtained from the oxidation of 6-chloro-4-(2-phenyl-ethen-yl)chroman-2-ol, which was synthesized by the reaction of of (E)-3-(5-chloro-2-hy-droxy-phen-yl)acryl-aldehyde with styrylboronic acid using diethyl-amine as a catalyst. The six-membered pyran-one ring of the chromane system has a screw-boat conformation. The dihedral angle between the least-squa...
متن کاملNovel synthesis of Pyrimido[4,5- e] [1,3,4] thiadiazines
Treatment of 1-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-1-methylhydrazine with dimethylthiocarbamoylchloride gave 7-chloro-N,N,1,5-tetramethyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-amine in basic acetonitrile. The latter compounds were reacted with secondary amines in boiling ethanol to afford the related 7-amino derivatives.
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